Crimean forest Normocardil - winthropdraycotttwの日記

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The active ingredient of Normocardil is propranolol. Propranolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). Propranolol hydrochloride is a stable, white, crystalline solid which is readily soluble in water and ethanol. Its molecular weight is 295.80. Propranolol Hydrochloride Extended-Release Capsules, USP, are formulated to provide sustained release of Propranolol hydrochloride. Propranolol Hydrochloride Extended-Release Capsules, USP, are available as 60mg, 80mg, 120mg, and 160mg capsules for oral administration. Each capsule for oral administration contains sugar spheres, ethylcellulose, hypromellose phthalate, povidone, diethyl phthalate, polyethylene glycol, titanium dioxide, ammonium hydroxide, potassium hydroxide, black iron oxide, and gelatin. The 80 mg, 120 mg, and 160 mg capsules contain red and yellow iron oxide. In addition, the 160 mg FD & C Blue capsules contain No. 2. These capsules comply with USP Dissolution Test 1. Propranolol Hydrochloride Extended-Release Capsules, USP, should not be considered a single mg-for-mg substitute for Propranolol levels achieved in the same dose (see DOSAGE AND ADMINISTRATION). When changing to Propranolol Hydrochloride Extended-Release Capsules, USP, Propranolol can be considered, especially to maintain the effectiveness of the dosing interval. In most clinical settings, however, such as hypertension or angina where there is little correlation between plasma levels and clinical effect, Propranolol Hydrochloride Extended-Release Capsules, USP, have been therapeutically equivalent to the same mg dose of the conventional Propranolol as assessed by 24- hour effects on blood pressure and 24-hour exercise responses of heart rate, systolic pressure, and rate pressure product. Effects of Propranolol on plasma volume appear to be minor and somewhat variable. In angina pectoris, Propranolol generally reduces the oxygen requirement of the heart by catecholamine-induced increases in the heart rate, systolic blood pressure, and the extent of myocardial contraction. Propranolol may increase oxygen deficiency, increased blood pressure, and increased blood pressure. The net physiologic effect of beta-adrenergic blockade is usually advantageous and is manifested during the exercise of increased activity. Propranolol exerts its antiarrhythmic effects in concentration associated with beta-adrenergic blockade, and this appears to be its main antiarrhythmic mechanism of action. In dosages greater than required for beta blockade, Propranolol also exerts a quinidine-like or anesthetic-like membrane action which affects the cardiac action potential. The significance of the membrane action in the treatment of arrhythmias is uncertain. The mechanism of the anti-migraine effect of Propranolol has not been established. Beta-adrenergic receptors have been demonstrated in the pial vessels of the brain.

Possible side effects of Normocardil include: Anxiety; body aches or bread; decreased awareness or responsiveness; dry mouth; hair loss; scaly skin.

Angina, Anxiety, Aortic Stenosis, Arrhythmia, Atrial Fibrillation, Benign Essential Tremor, Heart Attack, Hemangioma, High Blood Pressure, Intermittent Explosive Disorder, Migraine Prevention, Mitral Prolapse Valve, Panic Disorder, Performance Anxiety , Pheochromocytoma, Portal Hypertension, Delayed Dyskinesia, Thyrotoxicosis, Ventricular Tachycardia.

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- Hypertension. - Prophylaxis of stress angina attacks. - Long-term treatment after myocardial infarction. - Reduction or prevention of sympathetic-dependent rhythm disorders: sinus or junctional tachycardias, tachycardias of atrial fibrillations and flutters, certain tachycardias of ventricular origin. - Cardiovascular manifestations of hyperthyroidism and intolerance to replacement therapy for hypothyroidism. - Functional signs of obstructive cardiomyopathy. - Background treatment of migraine and facial pain. - Tremors in particular essential s.

- Hypertension, prophylaxis of exercise angina attacks, obstructive cardiomyopathy: 4 tablets daily in 2 doses (160 mg) on average. The treatment can possibly be initiated by 2 tablets. - Long-term treatment after myocardial infarction. Initial treatment: It should be instituted between the 5th and the 21st day after the acute episode of infarction; 1 40 mg tablet 4 times daily for 2 to 3 days. . Maintenance treatment: 4 tablets daily in 2 doses (160 mg per day). - Rhythmic disorders and hyperthyroidism: 1 to 2 tablets daily in several doses. - Migraines, facial pain, tremors: 1 to 3 tablets a day.

CONTRAINDICATED: - Hypersensitivity to propranolol. - Asthma and obstructive chronic bronchopneumopathies. - Cardiac insufficiency not controlled by the treatment. - Cardiogenic shock. - Atrioventricular blocks of the 2nd and 3rd degrees not paired. - Angor of Prinzmetal. - Sinus disease (including sinoatrial block). - Bradycardia (). - Phenomenon of Raynaud and peripheral arterial disorders. - Untreated pheochromocytoma. - Hypotension. - Antecedent of anaphylactic reaction. - Association with floctafenine, sultopride (see interactions). - In the context of primary and secondary prevention of digestive hemorrhages in cirrhotic patients: advanced hepatic insufficiency with hyperbilirubinemia, massive ascites, hepatic encephalopathy. DISCONTINUED: - This drug is generally not recommended when combined with amiodarone (see interactions). - Breast-feeding: Beta-blockers are excreted in the milk. The risk of developing hypoglycaemia and bradycardia has not been evaluated; therefore, as a precautionary measure, it should be avoided in breastfeeding women.

SPORTS The attention of athletes is drawn to the fact that this specialty contains an active ingredient that can induce a positive reaction of tests performed during doping controls.

WARNINGS Due to the presence of lactose, this drug is contraindicated in case of congenital galactosemia, glucose-galactose malabsorption syndrome or lactase deficiency..

- Known allergy to propranolol, or history of allergic reaction. - Asthma and COPD with congestion. - Heart failure. - Bradycardia. - Conduction disorders, peripheral circulatory disorders. - Very severe hepatic insufficiency. - In case of treatment with floctafenine, sultopride.

- Prevention of gastrointestinal bleeding by rupture of oesophageal varices (primary prevention) and their recurrence (secondary prevention) in patients with cirrhosis: the prevention of a first oesophageal varices rupture is limited to the ayelz patient wearing endoscopic examination reveals Esophageal varices of intermediate or large size (stage II or III).

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Possible side effects of Normocardil include: Anxiety; body aches or bread; decreased awareness or responsiveness; dry mouth; hair loss; scaly skin.

- Treatment of certain rhythm disorders: supraventricular (tachycardias, flutters and atrial fibrillations, junctional tachycardias) or ventricular (ventricular extrasystoles, ventricular tachycardias);

increased or decreased appetite hot flashes constipation; dizziness weight gain; an unpleasant taste in the mouth; slight weakness or fatigue headaches; nausea low blood pressure vision problems (eg blurred vision) dryness of the mouth drowsiness.

Suicidal or agitated behavior: people taking an antidepressant such as amitriptyline may experience restlessness (impatience, anxiety, aggression, strong emotions, sleep disturbances, and feeling not be themselves), or they may want to hurt themselves or someone else. If you notice a change in mood, behavior, thoughts or feelings felt by yourself or someone taking this medicine, contact a doctor immediately. Your doctor will exercise strict supervision that will target changes in your behavior, especially at the beginning of treatment or when the dose you are taking is increased or decreased.

Before using any medication, be sure to tell your doctor about any medical conditions or allergies you may have, medications you are using, and other important things about your health. Women should mention if they are pregnant or breastfeeding. These factors could influence how you should use this medicine.

75 mg Each round, orange, biconvex, film-coated tablet, engraved "75" on one side, contains 75 mg of amitriptyline hydrochloride. Non-medicinal ingredients: microcrystalline cellulose, croscarmellose sodium, magnesium stearate, fumed silica, hydroxypropyl methylcellulose, polyethylene glycol, titanium dioxide, carnauba wax, and sun yellow on aluminum substrate.